Smart Drugs II (Smart Drug Series, V. 2)
by John Morgenthaler, Steven Wm. Fowkes, Ward Dean
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Book Summary Information
Author: John Morgenthaler, Steven Wm. Fowkes, Ward DeanEdition: Paperback
Audio: English (Unknown); English (Original Language); English (Published)
Published: 1993
ISBN: 0962741876
Number of pages: 287
Publisher: Smart Publications
Book Reviews of Smart Drugs II (Smart Drug Series, V. 2)
Book Review: Chapter on ondansetron out of date and incomplete.
Summary: 1 Stars
As a user of Zofran(Ondansetron) and someone who has researched this drug extensively I find the information inadequate and out of date. For instance the oral form (8mg tablets) has been available for some time now. It was originally investigated as an anti-psychotic drug and tested as an alcohol and cocaine/methamphetmine deterent for which there was no clear cut outcomes as to efficacy. Dr. Michael Liebowitz at Columbia/New York Psychiatric Institute has done the most recent research on Zofran for Generalized Anxiety Disorder with positive results, however Glaxo has stopped clinical trials/research into Zofran for psychiatric uses sometime in winter 1996. There are some studies (small populations) showing efficacy of Zofran in Parkinson patients to control dilusions and hallucinations. The authors seem to have neglected to do a complete medline search on this medication which has been investigated since approximately 1989! There are significant side effects to this drug which should not be taken lightly. The literature recommends the medication be taken no more than two days in a row without medical supervision. It is extremely difficult to find information regarding appropriate dosages for the oral form in treating mental health problems (for which it is quite effective-without eps side effects).
The few pages in this book are so general and uninformative as to make it almost useless. Zofran is available only by prescription and then primarily for use with chemotherapy. It is also difficult to get IV Zofran unless you have cancer or an extremely enlightened physican. Zofran tablets at the pharmacy (US) cost approximately $23 each and most HMO's limit patient to 9 (8mg) tablets at a time. At this time it is not available in smaller dosages, although the tablets can be broken in half trying to get a smaller dose is extemely difficult. Attempts at getting information from Glaxo-Wellcome the manufacturer have been extremely difficult.
If the authors have been this lax in obtaining information about this drug it makes me suspicious of the thoroughness of the information researched for the other drugs. Remember there is no free lunch especially when dealing with pharmaceuticals. Weigh carefully potential side effects against possible benefit. This is not a "natural" product but a highly concentrated anti-psychotic, anti-emetic drug.
Summary of Smart Drugs II (Smart Drug Series, V. 2)
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